Order a medium coffee at two different chains, and you are not ordering the same drink. One barely clears a light pick-me-up. While the other can nearly max out what doctors call a safe day of caffeine, all in a single cup. Same size, give or take an ounce, yet the jolt depends on whose logo is on it, and sometimes on who did the measuring. Here are seven chains ranked by the caffeine in a medium, using the numbers the chains publish plus one independent lab test that checked the rest.

Starbucks Sits at the Top of the Chart
A grande Pike Place Roast, Starbucks’ standard 16-ounce cup, contains 315 to 390 milligrams of caffeine by the company’s own count. Even the low end beats every other chain here. One grande can bring you close to the 400 milligrams a day the FDA calls safe for most adults. Worth knowing: when Labdoor tested a medium Starbucks against its rivals, it measured about 267 milligrams, proving even the leader’s number slides around.
Caribou Keeps Pace With the Big Name
Caribou, the Minnesota-born chain, puts 305 milligrams in its 16-ounce medium brewed coffee. That sits right on Starbucks’ heels and ahead of every national name below it. If you grew up thinking of Caribou as the gentler Midwest option, the numbers say otherwise.
7-Eleven Punches Above Its Reputation
When Labdoor lab-tested two dozen medium cups from four national chains for BuzzFeed News, Starbucks didn’t win. It was 7-Eleven, averaging 280 milligrams, edging out the famous name in that same test. Your gas-station coffee may be stronger than the stuff brewing next door.

McDonald’s McCafé Holds Its Own
McDonald’s doesn’t list a caffeine number for its brewed coffee, so the only solid figure comes from that same lab test: about 227 milligrams in a medium McCafé. Not bad for a drive-thru afterthought, and ahead of a couple of chains that built their whole name on coffee.

Dunkin’ Runs Strong in a Smaller Cup
A medium at Dunkin’ is 14 ounces, not 16, and it still lands around 210 to 220 milligrams, depending on whether you go by Dunkin’s data or the lab test. Pour that into the same cup the others use and the number would climb. For a chain that leans on its coffee name, the caffeine backs up the talk.
Biggby Lands in the Middle
Biggby, another Midwest regular, lists 190 milligrams in its 16-ounce cup, its smallest hot size. That drops it mid-pack, close enough to the next chain that a single cup is basically a coin flip between them.
Panera Rounds Out the List
Panera’s 16-ounce regular coffee comes in at 189 milligrams, one milligram behind Biggby and, like several here, a figure the chain calls approximate. It is the lowest number on the list, though lowest still means nearly half the FDA’s daily max in one cup. No gentle sipper.
Let the Milligrams Guide the Order
Cup labels are branding, not a common unit of caffeine. Check the drink, ounces, and milligrams together, then count caffeine from tea, soda, energy products, chocolate, supplements, and medicines during the rest of the day. The FDA says 400 milligrams a day is an amount not generally associated with negative effects for most adults, but sensitivity and medical circumstances vary. A personal limit deserves more weight than a ranking.